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Application of Freeze Dryer in Cell Therapy

Application of Freeze Dryer in Cell Therapy

January 20, 2025

The application of freeze dryer in cell therapy is mainly reflected in the long-term preservation of cell activity, improving drug stability and optimizing drug delivery system. The following is the introduction of its specific applications:

 

1. Long-term preservation of cell activity

Protection of cell structural integrity: through freeze dry technology, the morphology and function of cells can be effectively preserved to avoid cell membrane rupture and organelle dysfunction caused by water crystallization.

Extend cell storage time: Ultra-low temperature freeze dryer can significantly extend the survival time of cells, which is crucial for cell samples that require long-term preservation.

Facilitates transportation and distribution: the reduced volume and weight of freeze dry cells facilitates long-distance transportation and mass storage, while reducing costs.

2. Improve drug stability

Reduces mechanical damage: Traditional liquid nitrogen freezing methods may result in mechanical damage to cells during crystallization, which is avoided with freeze drying.

Maintains biological properties: The biomolecules inside the cells are well protected during freeze-drying, which contributes to the stability of the cells when they are stored for a long period of time.

3. Optimize drug delivery system

Improve drug efficacy: Freeze-drying microsphere technology is widely used in the preparation of microspheres, nanoparticles and other new drug formulations. These new formulations have the advantages of high bioavailability, small dosage, low side effects, etc., which can significantly improve the efficacy of drugs and the patient's drug experience.

Gene therapy and cell therapy: In the field of biotechnology, freeze-drying microsphere technology is also used to prepare biological products for gene therapy and cell therapy. Through this technology, biological products such as live cells, proteins and genes can be stabilized and preserved for a long period of time, which facilitates the production, transportation and use of biological products.

Freeze-drying of diagnostic reagents: Freeze-drying microsphere technology has also been applied to the freeze-drying of nucleic acid diagnostic reagents, in vitro diagnostic reagents, pet in vitro diagnostic reagents and so on. These freeze dry reagents are of high quality, stability and quantitative, and can be stored for a long time at room temperature, which is convenient for transportation and use.

Overall, the application of freeze dryer in the field of cell therapy not only improves the survival rate and activity of cells, but also promotes the innovation and development of drug delivery systems. With the continuous progress and improvement of technology, freeze dry technology will play a more important role in cell therapy in the future.


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