For the application of liquid nitrogen biological tanks, the main reason is that the liquid nitrogen stored in the tank produces an ultra-low-temperature environment, which can be used for the frozen storage of food, biological cells and so on. The reason why liquid nitrogen can create an ultra-low temperature environment is mainly due to its boiling point of -196.56 ℃ at atmospheric pressure, 1 cubic meter of liquid nitrogen can be expanded to 696 cubic meters of pure gaseous nitrogen, which can make the surrounding environment instantly to -196 ℃, creating an ultra-low temperature environment.

According to a report issued by the World Health Organization, approximately 50% of vaccines are wasted globally each year during transportation and distribution due to substandard temperature control . In the United States, the Centers for Disease Control and Prevention (CDC) and the World Health Organization recommend: establishing an implementation plan for cryogenic storage and temperature monitoring based on the purpose of the application, making effective use of the limited global supply of cryogenic storage equipment, and protecting the integrity of vaccines.

Temperature control of the storage of samples, strains, production materials and final products also plays a key role in the development and production of vaccines, and the reliability of samples depends on the reliability of their storage units.

The advantages of liquid nitrogen tanks in storing virus and vaccine strains include the following:

1. Ultra-low temperature environment: Liquid nitrogen tanks can provide extremely low temperatures of about -196°C, which is much lower than the temperature of a typical refrigerator or freezer, and can effectively freeze and preserve viruses and vaccine strains, maintaining their activity and stability.

2. Preventing oxidation and moisture: the pressure inside the liquid nitrogen tank is lower than atmospheric pressure, which can reduce the entry of oxygen and moisture, thus preventing the deterioration of samples caused by oxidation and moisture, maintaining the quality of the samples and prolonging the preservation time.

3. Long-term preservation ability: liquid nitrogen tanks can provide long time cryopreservation, suitable for preserving various viruses and vaccine strains, and some samples can even be preserved for years or even decades, ensuring the long-term preservation quality of the samples.

4.High capacity and flexibility: The liquid nitrogen tanks are available in different capacities and sizes, so you can choose the right model according to the actual needs. It is easy and flexible to use, and samples can be added or removed at any time, which is very suitable for scientific research experiments and other situations that require frequent operation.

5. Sealing and safety: liquid nitrogen tanks are well sealed, which can reduce the impact on the surrounding environment and ensure the stability of liquid nitrogen. Meanwhile, equipped with valves and pressure sensors, it can detect abnormal pressure in time and issue an alarm to improve the safety of use.

These characteristics make liquid nitrogen tanks play an irreplaceable role in the long-term storage and transportation of viruses and vaccine strains, ensuring the quality and efficacy of vaccines, which is of great significance to global public health security.